Zeamatin inhibits trypsin and alpha-amylase activities

Applied and Environmental Microbiology
R Schimoler-O'RourkeC P Selitrennikoff

Abstract

Zeamatin is a 22-kDa protein isolated from Zea mays that has antifungal activity against human and plant pathogens. Unlike other pathogenesis-related group 5 proteins, zeamatin inhibits insect alpha-amylase and mammalian trypsin activities. It is of clinical significance that zeamatin did not inhibit human alpha-amylase activity and inhibited mammalian trypsin activity only at high molar concentrations.

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Citations

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