Zebrafish mutants of the neuromuscular junction: swimming in the gene pool

The Journal of Physiological Sciences : JPS
Eriko DaikokuFumihito Ono

Abstract

This review provides an overview of zebrafish mutants with dysfunctional acetylcholine receptors or related proteins at the neuromuscular junction (NMJ). The NMJ, which has served as the classical model of the chemical synapse, uses acetylcholine as the neurotransmitter, and mutations of proteins involved in the signaling cascade lead to a variety of behavioral phenotypes. Mutants isolated after random chemical mutagenesis screening are summarized, and advances in the field resulting from these mutants are discussed.

References

Apr 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·C G JenningsS J Burden
Mar 7, 1998·Genes & Development·S J Burden
Jan 16, 2002·American Journal of Human Genetics·Kinji OhnoMargherita Milone
May 7, 2004·Development·Julie L LefebvreMichael Granato
Jun 18, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Fumihito OnoPaul Brehm
Aug 19, 2005·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Axel Meyer, Yves Van de Peer
Jan 20, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jessica A PanzerRita J Balice-Gordon
Apr 4, 2006·Current Biology : CB·Ian G WoodsWilliam S Talbot
Jun 24, 2006·Science·Kumiko OkadaYuji Yamanashi
Feb 8, 2007·Proceedings of the National Academy of Sciences of the United States of America·Julie L LefebvreMichael Granato
Feb 7, 2008·American Journal of Human Genetics·Anne MichalkKatrin Hoffmann
Oct 14, 2008·Cell·Natalie KimSteven J Burden
Nov 7, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Lucia S BorgesMichael J Ferns
Dec 5, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Kimberly E EpleyFumihito Ono
May 25, 2012·Nature·Misha B AhrensRuben Portugues
May 25, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jee-Young ParkFumihito Ono
Jun 8, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael WalogorskyPaul Brehm
Oct 10, 2012·Proceedings of the National Academy of Sciences of the United States of America·Michael WalogorskyPaul Brehm
Apr 26, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hua WenPaul Brehm
May 10, 2013·PloS One·Hiromi IkedaFumihito Ono
Aug 1, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jee-Young ParkFumihito Ono

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Citations

Mar 10, 2016·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Takahiro Hasumura, Shinichi Meguro
Nov 17, 2015·Cell & Bioscience·Victor M LunaFumihito Ono
Jan 28, 2021·Cells·Maria-Letizia CampanariEdor Kabashi

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