Zebrin Expression in the Cerebellum of Two Crocodilian Species.

Brain, Behavior and Evolution
Cristian Gutierrez-IbanezDouglas R W Wylie

Abstract

While in birds and mammals the cerebellum is a highly convoluted structure that consists of numerous transverse lobules, in most amphibians and reptiles it consists of only a single unfolded sheet. Orthogonal to the lobules, the cerebellum is comprised of sagittal zones that are revealed in the pattern of afferent inputs, the projection patterns of Purkinje cells, and Purkinje cell response properties, among other features. The expression of several molecular markers, such as aldolase C, is also parasagittally organized. Aldolase C, also known as zebrin II (ZII), is a glycolytic enzyme expressed in the cerebellar Purkinje cells of the vertebrate cerebellum. In birds, mammals, and some lizards (Ctenophoresspp.), ZII is expressed in a heterogenous fashion of alternating sagittal bands of high (ZII+) and low (ZII-) expression Purkinje cells. In contrast, turtles and snakes express ZII homogenously (ZII+) in their cerebella, but the pattern in crocodilians is unknown. Here, we examined the expression of ZII in two crocodilian species (Crocodylus niloticus and Alligator mississippiensis) to help determine the evolutionary origin of striped ZII expression in vertebrates. We expected crocodilians to express ZII in a striped (ZII+/ZII-...Continue Reading

References

May 1, 1992·Biochemical Society Transactions·R Hawkes
Jun 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·N LeclercM Yamamoto
Apr 8, 1991·The Journal of Comparative Neurology·J J Arends, H P Zeigler
Apr 10, 1983·The Journal of Comparative Neurology·G C BangmaA Pellegrino
Jun 1, 1983·The Journal of Comparative Neurology·I E Schwarz, D W Schwarz
Jan 1, 1981·Cell and Tissue Research·S O Ebbesson, D C Goodman
Jan 1, 1997·Annual Review of Neuroscience·K Herrup, B Kuemerle
Feb 9, 2002·The Journal of Comparative Neurology·Miguel SanchezRichard Hawkes
Feb 20, 2003·Brain Research·Matt LaroucheRichard Hawkes
Jun 6, 2003·Brain Research·Roy V SillitoeRichard Hawkes
Jan 22, 2005·Progress in Brain Research·Roy V SillitoeRichard Hawkes
May 24, 2006·Brain, Behavior and Evolution·Andrew N IwaniukDouglas R W Wylie
Nov 17, 2006·Brain, Behavior and Evolution·Andrew N IwaniukDouglas R W Wylie
Dec 22, 2006·The Journal of Comparative Neurology·Izumi Sugihara, Pham Nguyen Quy
Feb 6, 2007·The Journal of Comparative Neurology·Janelle M P PakanHassan Marzban
Apr 17, 2007·The Journal of Comparative Neurology·Holly R CampbellCurtis C Bell
Sep 7, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Izumi Sugihara, Yoshikazu Shinoda
Aug 21, 2009·Nature Reviews. Neuroscience·Richard Apps, Richard Hawkes
Sep 5, 2009·The Journal of Comparative Neurology·Ji-Young KimRichard Hawkes
Nov 26, 2009·The Journal of Comparative Neurology·Janelle M P PakanDouglas R Wylie
May 4, 2010·The Journal of Comparative Neurology·Hassan MarzbanRichard Hawkes
May 28, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Martin PaukertDwight E Bergles
Jul 2, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Abteen MostofiSteve A Edgley
Sep 15, 2010·The Cerebellum·Hassan Marzban, Richard Hawkes
Nov 26, 2010·Brain, Behavior and Evolution·Masato FurueMasato Uehara
Sep 1, 1998·Trends in Cognitive Sciences·J Voogd, M Glickstein
May 4, 2011·Annals of the New York Academy of Sciences·Jeroen B SmaersKarl Zilles
Nov 23, 2011·The Journal of Comparative Neurology·Douglas R WylieAndrew N Iwaniuk
Sep 14, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·David J Graham, Douglas R Wylie
Aug 13, 2013·Journal of Chemical Neuroanatomy·Douglas R WylieAndrew N Iwaniuk
May 21, 2014·ELife·Haibo ZhouMartijn Schonewille

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