Zika virus infection and implications for kidney disease

Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte
Donald J Alcendor

Abstract

High-level and persistent viruria observed in patients infected by Zika virus (ZIKV) has been well documented. However, renal pathology in acutely infected, immunocompetent patients remains subclinical. Moreover, the long-term impact of ZIKV infection, replication, and persistence in the renal compartment of adults and infants as well as immunosuppressed patients and solid organ transplant (SOT) recipients is unknown. Mechanisms involving host and viral factors that limit or control ZIKV pathogenesis in the renal compartment are important yet unexplored. The observation that long-term viral shedding occurs in the renal compartment in the absence of clinical disease requires further investigation. In this review, I explore Zika virus-induced renal pathology in animal models, the dynamics of virus shedding in urine, virus replication in glomerular cells, ZIKV infection in human renal transplantation, and the potential impact of long-term persistent ZIKV infection in the renal compartment.

References

Dec 31, 2002·Physiological Reviews·Hermann PavenstädtMatthias Kretzler
Aug 14, 2003·American Journal of Nephrology·Laura Barisoni, Peter Mundel
Sep 1, 1952·Transactions of the Royal Society of Tropical Medicine and Hygiene·G W A DICKA J HADDOW
Mar 1, 1954·Transactions of the Royal Society of Tropical Medicine and Hygiene·F N MACNAMARA
Aug 6, 2008·Emerging Infectious Diseases·Robert S LanciottiMark R Duffy
Dec 18, 2008·Neuroepidemiology·Anita McGroganCorinne S de Vries
Oct 1, 2009·Emerging Infectious Diseases·Edward B Hayes
Jan 15, 2014·PLoS Neglected Tropical Diseases·Oumar FayeAmadou Alpha Sall
Oct 9, 2014·The American Journal of Tropical Medicine and Hygiene·Kevin FonsecaRaymond Tellier
Dec 23, 2014·Emerging Infectious Diseases·Ann-Claire GourinatMyrielle Dupont-Rouzeyrol
Jun 11, 2015·Memórias do Instituto Oswaldo Cruz·Camila ZanlucaKleber Luz
Sep 26, 2015·Emerging Infectious Diseases·Didier Musso
Jan 18, 2016·Microbes and Infection·Jason A Tetro
Jan 29, 2016·MMWR. Morbidity and Mortality Weekly Report·Lavinia Schuler-FacciniUNKNOWN Brazilian Medical Genetics Society–Zika Embryopathy Task Force
Feb 13, 2016·MMWR. Morbidity and Mortality Weekly Report·Alexandra M OsterLyle R Petersen
Feb 28, 2016·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Renata de M CamposDavis F Ferreira
Mar 12, 2016·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Benoît RozéUNKNOWN GBS Zika Working Group
Mar 30, 2016·The American Journal of Tropical Medicine and Hygiene·Shannan L RossiScott C Weaver
Apr 14, 2016·Cell Host & Microbe·Helen M LazearMichael S Diamond
May 5, 2016·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·S N SlavovD T Covas
May 12, 2016·Kidney International·Michio Nagata
May 18, 2016·The Lancet Infectious Diseases·Fu-Chun ZhangCheng-Feng Qin
May 24, 2016·PLoS Neglected Tropical Diseases·Matthew T AliotaJorge E Osorio
Feb 9, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Carolina Peralta-Aros, Víctor García-Nieto
Mar 10, 2017·PLoS Pathogens·Alec J HirschDaniel N Streblow
Mar 24, 2017·Acta Neuropathologica·Leila ChimelliAmilcar Tanuri
Jul 28, 2017·Current Opinion in Virology·Christina NewmanDavid H O'Connor
Aug 16, 2017·Virus Research·Jessica L Kublin, James B Whitney
Aug 27, 2017·Scientific Reports·André C FerreiraThiago Moreno L Souza
Oct 20, 2017·Emerging Infectious Diseases·Ana Carolina B TerzianMaurício L Nogueira
Dec 1, 2017·Travel Medicine and Infectious Disease·Haimei JiaTie Song
Dec 22, 2017·The Journal of Infectious Diseases·Christa E Osuna, James B Whitney
Mar 2, 2018·PloS One·Lucia Maria Costa MonteiroMaria Elizabeth Lopes Moreira

❮ Previous
Next ❯

Citations

May 10, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Fahad AzizDidier Mandelbrot
Nov 1, 2020·Pathogens·Sophie MasmejanDavid Baud
Apr 4, 2021·International Journal of Molecular Sciences·Alawiya ReslanGilles Gadea

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsies
antibody assay

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Related Papers

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Sora Yasri, Viroj Wiwanitkit
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Regis A VilchezShimon Kusne
Transplant Infectious Disease : an Official Journal of the Transplantation Society
C CerveraA Moreno
© 2022 Meta ULC. All rights reserved