Zinc, an unexpected integrator of metabolism?

Microbial Biotechnology
Antoine Danchin

Abstract

Even when they no longer require the presence of iron, cells use zinc as a divalent cation, involved in a large variety of catalytic and regulatory functions. This metal is so important that it appears that ribosomes are instrumental in its ultimate storage. Here, we summarize a detailed analysis which investigates the way the global cell metabolism is integrated by zinc. This integration results from the zinc-dependent way in which the one-carbon metabolism is always coupled to the translation process, not only via methionine and S-adenosylmethionine, but via the complex set-up of the modification of the position 34 of the anticodon of tRNAs.

References

Mar 1, 1975·Metabolism: Clinical and Experimental·M E MaguireA G Gilman
May 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·M Tao, F Lipmann
Aug 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·P C Sternweis, A G Gilman
Jul 17, 1998·Current Opinion in Chemical Biology·J E Coleman
May 20, 1959·The Journal of General Physiology·P ELSBACH, I L SCHWARTZ
Aug 25, 2009·Accounts of Chemical Research·Claudia AndreiniAntonio Rosato
Dec 27, 2011·Journal of Inorganic Biochemistry·M Patrick HensleyMichael W Crowder
Apr 28, 2016·Archives of Biochemistry and Biophysics·Artur Krężel, Wolfgang Maret
Sep 13, 2016·Annual Review of Genetics·Lauren D Palmer, Eric P Skaar
Oct 8, 2016·Journal of Microbiology and Biotechnology·Ki Seong EomSeung Jae Lee
Mar 17, 2017·Topics in Current Chemistry·Yi JinG Michael Blackburn
Nov 22, 2017·Journal of Inorganic Biochemistry·Yana ValasatavaClaudia Andreini
May 22, 2019·Journal of Bacteriology·Lucy BütofDietrich H Nies
Jun 21, 2019·Molecular Microbiology·Dietrich H Nies
Oct 28, 2019·Frontiers in Plant Science·Catalina CabotCharlotte Poschenrieder
Nov 22, 2019·Nature Reviews. Microbiology·Jos KramerRolf Kümmerli
Dec 11, 2019·International Journal of Molecular Sciences·Hyewon SeoCheol-Won Yun
Jan 7, 2020·IScience·Mike BroedersW W M Pim Pijnappel
Mar 11, 2020·Microbial Biotechnology·Antoine DanchinConghui You

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