Zinc deficiency during the latter third of pregnancy: effects on fetal rat brain, liver, and placenta
The effects of zinc deficiency during the last third of gestation on the growth and development of the fetal rat at term were investigated. Zinc deficiency resulted in anorexia and weight loss of the pregnant dams. Fetuses from such dams displayed intrauterine growth retardation when compared with fetuses from pair-fed or ad libitum-fed controls given adequate zinc. Although the brains of the zinc-deficient fetuses were smaller than those of the controls, the brain was relatively spared while the liver was severely affected. The total cell number was reduced and there was an apparent increase in cell size in the brains of zinc-deficient fetuses in comparison with the brains of the controls. The growth failure of the zinc-deficient liver resulted in a smaller complement of total DNA, RNA, protein, and lipid, and there was less incorporation of [3H]thymidine into DNA in the liver. The placenta appeared to be only marginally affected by the zinc deficiency.
Effects of prenatal nutritional deficiency on discrimination learning in rats: acquisition and retention
Methionine metabolism in isolated perfused livers from rats fed on zinc-deficient and restricted diets
Incorporation of(3)H-thymidine into DNA and the activity of alkaline phosphatase in zinc-deficient fetal rat brains
Effects of maternal marginal zinc deficiency on myelin protein profiles in the suckling rat and infant rhesus monkey
Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.