Zinc deficiency in pregnancy and fetal outcome

Nutrition Reviews
Dheeraj Shah, H P S Sachdev

Abstract

Maternal zinc deficiency during pregnancy has been related to adverse effects on progeny, and there are data showing that mild to moderate zinc deficiency (as assessed by available indicators) is quite common in the developing world. Observational data relating zinc deficiency to adverse fetal outcome have produced conflicting results, mainly because of the lack of a valid indicator of zinc deficiency in pregnancy. Studies of human pregnancy and zinc supplementation, including those from developing countries, have failed to document a consistent beneficial effect on fetal growth, duration of gestation, and early neonatal survival. Preliminary results from unpublished studies in developing countries have also proven to be discouraging. However, recent data and some preliminary findings indicate a beneficial effect of maternal zinc supplementation on neonatal immune status and infant morbidity from infectious diseases, and there is also preliminary evidence that, zinc supplementation may prevent congenital malformations (cleft lip/palate). With respect to neurobehavioral development, the evidence is conflicting, with only one study reporting a positive outcome. More research is required to assess the benefits of the large-scale i...Continue Reading

References

Mar 1, 1992·The American Journal of Clinical Nutrition·M S GolubB Lönnerdal
Jan 1, 1991·Gynecologic and Obstetric Investigation·A O CavdarH Yavuz
Oct 1, 1991·The American Journal of Clinical Nutrition·A KirkseyN W Jerome
Aug 1, 1991·Journal of Public Health Medicine·J S RobertsonS M Atkinson
Jan 1, 1990·Progress in Brain Research·C J Frederickson, G Danscher
Sep 30, 1989·BMJ : British Medical Journal·K MahomedR McCabe
Nov 1, 1989·The American Journal of Clinical Nutrition·F F CherryX B Wang
Jun 1, 1988·The American Journal of Clinical Nutrition·M S GolubA G Hendrickx
Jan 1, 1986·Gynecologic and Obstetric Investigation·G Kynast, E Saling
Sep 1, 1985·British Journal of Obstetrics and Gynaecology·M Campbell-BrownJ C King
Dec 1, 1985·The American Journal of Clinical Nutrition·M S GolubW Y Saito
Apr 21, 1973·Lancet·L E Sever
Jun 9, 1973·Lancet·J A Halsted
Apr 1, 1970·The Journal of Nutrition·J Apgar
Jul 1, 1968·The American Journal of Physiology·J Apgar
Dec 1, 1966·Proceedings of the Society for Experimental Biology and Medicine·L S Hurley, H Swenerton
Dec 1, 1984·The American Journal of Clinical Nutrition·M S GolubA G Hendrickx
Jun 1, 1984·The American Journal of Clinical Nutrition·M S GolubA G Hendrickx
Oct 1, 1983·The American Journal of Clinical Nutrition·R S BeachL S Hurley
Jun 1, 1982·The Journal of Nutrition·R S BeachL S Hurley
Aug 1, 1980·The American Journal of Clinical Nutrition·J E MorleyJ M Hershman
Aug 1, 1995·The Journal of Nutrition·M S GolubA G Hendrickx
Aug 9, 1995·JAMA : the Journal of the American Medical Association·R L GoldenbergJ C Hauth
Feb 1, 1995·Seminars in Perinatology·D M OlsonD W Sadowsky
Jan 1, 1994·Advances in Experimental Medicine and Biology·G E BunceC Kim
Oct 17, 1994·The Medical Journal of Australia·A J McMichaelE F Robertson
Nov 1, 1994·The American Journal of Clinical Nutrition·A KirkseyN W Jerome
Sep 1, 1994·Archives of Pediatrics & Adolescent Medicine·B SandströmB Lönnerdal
Aug 1, 1993·Australian and New Zealand Journal of Medicine·C J Kilpatrick, J L Hopper
Aug 1, 1993·British Journal of Obstetrics and Gynaecology·M HambidgeN Wald
Jan 1, 1993·Physiological Reviews·B L Vallee, K H Falchuk
Mar 15, 1993·Annals of the New York Academy of Sciences·C L KeenM E Gershwin
Sep 1, 1996·Acta Obstetricia Et Gynecologica Scandinavica·B JønssonF Hald
Aug 13, 1998·The American Journal of Clinical Nutrition·P Christian, K P West
Aug 13, 1998·The American Journal of Clinical Nutrition·P Whittaker
Aug 13, 1998·The American Journal of Clinical Nutrition·L E CaulfieldM Merialdi
Feb 13, 1999·American Journal of Obstetrics and Gynecology·M MerialdiJ A DiPietro
Jun 5, 1999·The American Journal of Clinical Nutrition·L E CaulfieldA Figueroa

Citations

Mar 14, 2013·Annals of Maxillofacial Surgery·Fadekemi O Oginni, Anthony T Adenekan
Nov 13, 2009·Nutrition Reviews·Susanna Cunningham-RundlesJeffrey M Perlman
Nov 11, 2011·Journal of Assisted Reproduction and Genetics·E H DickersonS L Atkin
Oct 6, 2007·Biological Trace Element Research·Thomas A TompkinsAkira Kiuchi
Dec 3, 2010·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Raúl BallestínXavier Ponsoda
Jun 8, 2007·Maternal and Child Health Journal·George L Wehby, Jeffrey C Murray
May 21, 2011·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Emily HoRobert L Tanguay
Jul 10, 2009·The British Journal of Oral & Maxillofacial Surgery·K K HozyaszM Szymanski
Dec 11, 2008·Birth Defects Research. Part A, Clinical and Molecular Teratology·Ronald G MungerJohn C Carey
Aug 31, 2010·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Janet Y Uriu-Adams, Carl L Keen
Jul 7, 2012·Paediatric and Perinatal Epidemiology·Guoyao WuAmy Webb Girard
Jun 13, 2015·The Cochrane Database of Systematic Reviews·Sheena DerryPhilip J Wiffen
Mar 27, 2007·Public Health Nutrition·Guansheng MaXiaoguang Yang
Oct 11, 2012·Public Health Nutrition·Sun Eun LeeL E Caulfield
Apr 15, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Joe Leigh SimpsonWolfgang Holzgreve
Sep 2, 2019·Biological Trace Element Research·Yanping HuangMin Kong
May 14, 2020·Chembiochem : a European Journal of Chemical Biology·Mai PhilipsenAndrew G Ewing
Oct 21, 2006·Current Opinion in Clinical Nutrition and Metabolic Care·Manuel Ruz
Mar 15, 2016·Frontiers in Physiology·Madeleine L BurgJane C Figueiredo
Aug 11, 2018·Prenatal Diagnosis·Ewa ParfieniukMonika Zbucka-Kretowska
Nov 27, 2014·Human & Experimental Toxicology·P SenguptaS Banerjee
Dec 2, 2015·The American Journal of Tropical Medicine and Hygiene·Brittany L KmushKenrad Nelson
Feb 23, 2011·The British Journal of Nutrition·Yo A LeeNamsoo Chang
Jun 10, 2016·The Cochrane Database of Systematic Reviews·Dheeraj ShahJuan Pablo Peña-Rosas
Feb 15, 2015·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Callum Livingstone
Mar 7, 2021·Nutrients·Marie JouanneAnne Sophie Voisin-Chiret

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.