Zinc for Acute Diarrhea and Amoxicillin for Pneumonia, Do They Work? : Delivered at the AIIMS, IJP Excellence Award for the year 2013 on 7th September 2014

Indian Journal of Pediatrics
Archana Patel

Abstract

Acute diarrhea and pneumonia are the two largest killers of under-five children in the world. Zinc, used in management of acute diarrhea and Amoxicillin, used in community acquired pneumonia, feature in the list of 13 Life Saving Commodities for Women's and Children Health by the UN Commission. Zinc has caught wide scientific attention for the conceptual promise it has to offer for prevention, control and treatment of acute diarrhea. This presentation focuses on author's research on the mechanisms by which zinc might contribute to the pathogenesis of acute diarrhea and the degree of success achieved in diarrhea control and treatment by zinc supplementation including its impact on mortality. However, emerging evidence in terms of controlled studies in humans beckons a more complete understanding of the mechanistic basis for zinc supplementation. Current evidence indicates that studies specifically addressing the variability in response to zinc supplementation need to be undertaken to better comprehend these mechanisms. Similarly, the author presented her research that examined the role of oral amoxicillin in community management of severe pneumonia in children and the need to assess its universal efficacy in all children with se...Continue Reading

References

Jan 8, 2008·Lancet·Tabish HazirUNKNOWN New Outpatient Short-Course Home Oral Therapy for Severe Pneumonia Study Group
Oct 31, 2009·Bulletin of the World Health Organization·Christa L Fischer WalkerRobert E Black
Jul 2, 2010·International Journal of Pediatrics·Archana B PatelHemant Kulkarni
Dec 15, 2011·Current Infectious Disease Reports·Hemant KulkarniArchana Patel

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Citations

Dec 22, 2017·São Paulo Medical Journal = Revista Paulista De Medicina·Vinícius Lopes BragaRachel Riera
Feb 13, 2021·Medical Sciences : Open Access Journal·Randal K BuddingtonScott C Howard

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