Zinc levels after iron supplementation in patients with chronic kidney disease

Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation
Denise MafraSlvia M F Cozzolino

Abstract

The goal of this study was to evaluate the effects of iron supplementation on zinc distribution in nondialyzed chronic kidney disease (CKD) patients. Prospective nonrandomized observational study. Outpatients of the Nephrology Division at Federal University of São Paulo. Zinc and iron status of 38 nondialyzed patients (63% male; creatinine clearance, 34.5+/-13.3 mL/min/1.73 m2) was evaluated before and after 3 intramuscular injections of 100 mg iron each. The following parameters were analyzed: erythrocytes and plasma zinc, zinc protoporphyrin (ZPP), plasma ferritin, transferrin saturation (TFS), and total iron. The patients' diets were analyzed by the Association of Official Analytical Chemists method for macronutrients, and neutron activation analysis was used for iron and zinc concentration determinations. Ferritin and TFS increased from 86.3+/-67.5 ng/mL to 105.4+/-63.7 ng/mL and from 19.5+/-7.4% to 23.2+/-6.7% (P <.05), respectively, after iron supplementation. Absolute iron deficiency (ferritin <100 microg/L and TFS <20%) was present in 41% of the patients and decreased to 15.7% after iron treatment. In comparison with baseline values (76.4+/-16.7 microg/dL), there were no significant changes in plasma zinc levels, but af...Continue Reading

References

Jan 1, 1985·Kidney International·B J MaroniW E Mitch
Jul 1, 1972·Journal of Chronic Diseases·A KeysH L Taylor
Mar 1, 1995·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S Fishbane, R I Lynn
Jan 1, 1994·Acta Haematologica·S Garrett, M Worwood
Mar 1, 1996·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J BraunW H Hörl
Mar 1, 1996·Biological Trace Element Research·T H LinJ G Juang
Jan 27, 1998·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·D I FávaroV L Tramonte
Mar 20, 1999·Kidney International. Supplement·D S SilverbergA Iaina
Oct 14, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·F Valderrábano
Dec 17, 2003·Clinical Biochemistry·Denise Mafra, Silvia M F Cozzolino

❮ Previous
Next ❯

Citations

Dec 24, 2010·Seminars in Dialysis·Richard K Kasama
May 18, 2020·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ludmila F M F Cardozo, Denise Mafra

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Related Papers

Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation
Carla Maria AvesaniLilian Cuppari
Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation
Vincenzo BellizziLuca Scalfi
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
H KastarinenY A Kesäniemi
Scandinavian Journal of Clinical and Laboratory Investigation
H KastarinenO Ukkola
© 2022 Meta ULC. All rights reserved