PMID: 9537309Apr 16, 1998Paper

Zinc supplementation, mental development and behaviour in low birth weight term infants in northeast Brazil

European Journal of Clinical Nutrition
A AshworthSally M Grantham-McGregor

Abstract

To test whether zinc supplementation reduces the deficits in mental development and behaviour that are found in term infants of low birth weight in the study population. A prospective double-blind, part-randomised efficacy trial. A low-income population in Pernambuco, northeast Brazil, where the economy is largely dependent on sugar-cane production, and where over 90% of deliveries occur in health facilities. During a 20-month period, all singleton, term infants weighing 1500-2499 g born to families of low income ( < US $280/month) were enrolled at birth (n = 205). At 6 and 12-months, the numbers tested were 163 and 138 respectively. Infants born from January 1993-January 1994 were randomly assigned to receive daily, except Sundays, a placebo (n = 66) or 1 mg zinc (n = 68). Those born February-August 1994 were given 5 mg zinc (n = 71). Supplementation was for eight weeks, starting at birth. Field workers visited each infant at home to administer the supplement. At 6 and 12-months, mental and psychomotor development was assessed with the Bayley Scales of Infant Development and no significant differences in the scores of the three groups were found. At 12-months, behaviour was also assessed on 5 ratings. Ratings were highest in i...Continue Reading

Citations

Feb 3, 2009·Biological Trace Element Research·S Tahmasebi BoroujeniM Javadian
Mar 4, 2011·Biological Trace Element Research·Ziba VaghriClyde Hertzman
Mar 3, 2004·Archives of Biochemistry and Biophysics·Bruce N Ames
Jun 2, 2005·Progress in Neurobiology·Eugenio MocchegianiMarco Malavolta
Sep 11, 2013·Revue D'épidémiologie Et De Santé Publique·H TraoreP Van de Perre
Jan 5, 2002·Early Human Development·E DoménechC Cortabarria
Oct 3, 2001·Acta Obstetricia Et Gynecologica Scandinavica·L SuttonD J Henderson-Smart
Aug 8, 2006·Nature Immunology·Hidemitsu KitamuraToshio Hirano
Aug 18, 2001·The British Journal of Nutrition·S Bhatnagar, S Taneja
Nov 10, 2004·The British Journal of Nutrition·Henrik FriisKim Fleischer Michaelsen
Feb 17, 2006·Public Health Nutrition·G P ChorghadeC H D Fall
Mar 17, 2007·Population Studies·John BlackerGareth Jones
Jan 30, 2009·The American Journal of Clinical Nutrition·Ann M DiGirolamo, Manuel Ramirez-Zea
Aug 28, 2012·Epigenomics·Keith E LathamNora Engel
Jul 31, 2013·Biological Trace Element Research·José Edson de MouraJosé Brandão-Neto
Mar 7, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·K M EdmondS O Agyei
Apr 21, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Nguyen Thanh Hien, Hiroshi Ushijima
Jun 19, 2004·Neurotoxicology and Teratology·Philip W DavidsonGregory E Wilding
Nov 27, 2015·Maternal & Child Nutrition·Leila Margaret Larson, Aisha K Yousafzai
Mar 27, 2010·BMC Pregnancy and Childbirth·Fernando C BarrosUNKNOWN GAPPS Review Group
Jul 22, 2016·PloS One·Rachel A BlakeJennifer F Friedman
Aug 28, 2013·The Journal of Physical Chemistry. a·Angélica Moreno BetancourtRosana M Romano
Jun 3, 2010·The Journal of International Medical Research·S MagginiD Hornig
Apr 19, 2012·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Roshan T RamlalUNKNOWN BAN Study Team
Dec 14, 2012·The Cochrane Database of Systematic Reviews·Siddhartha Gogia, Harshpal S Sachdev
Nov 17, 2011·European Journal of Clinical Nutrition·S K ThakurD Sarker
Jun 15, 2004·The Pediatric Infectious Disease Journal·Adam RothPeter Aaby
Oct 22, 2008·Annals of Human Biology·Ali DelpishehBernard J Brabin
Aug 16, 2018·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ramkumar MohanEmilyn Uy Alejandro
Sep 28, 2006·Tropical Medicine & International Health : TM & IH·Renée LarocqueTheresa W Gyorkos
Oct 30, 2007·Birth Defects Research. Part C, Embryo Today : Reviews·Lei Wang, Kent E Pinkerton
Jul 31, 2001·European Journal of Clinical Nutrition·F H VerhoeffR L Broadhead
Jun 30, 2015·Nature Medicine·Marc Veldhoen, Cristina Ferreira

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