Zinc(II) salphen complex-based fluorescence optical sensor for biogenic amine detection

Analytical and Bioanalytical Chemistry
Muhammad Ameerullah SahudinNurul Huda Abd Karim

Abstract

Biogenic amines have attracted interest among researchers because of their importance as biomarkers in determining the quality of food freshness in the food industry. A rapid and simple technique that is able to detect biogenic amines is needed. In this work, a new optical sensing material for one of the biogenic amines, histamine, based on a new zinc(II) salphen complex was developed. The binding of zinc(II) complexes without an electron-withdrawing group (complex 1) and with electron-withdrawing groups (F, complex 2; Cl, complex 3) to histamine resulted in enhancement of fluorescence. All complexes exhibited high affinity for histamine [binding constant of (7.14 ± 0.80) × 104, (3.33 ± 0.03) × 105, and (2.35 ± 0.14) × 105 M-1, respectively]. Complex 2 was chosen as the sensing material for further development of an optical sensor for biogenic amines in the following step since it displayed enhanced optical properties in comparison with complexes 1 and 3. The optical sensor for biogenic amines used silica microparticles as the immobilisation support and histamine as the analyte. The optical sensor had a limit of detection for histamine of 4.4 × 10-12 M, with a linear working range between 1.0 × 10-11 and 1.0 × 10-6 M (R2 = 0.98...Continue Reading

References

Jul 18, 2000·International Journal of Food Microbiology·L Lehane, J Olley
Sep 24, 2004·Journal of Chromatography. a·Judite Lapa-Guimarães, Jana Pickova
May 4, 2006·Journal of the American Chemical Society·Julie E ReedRamón Vilar
Dec 22, 2009·Dalton Transactions : an International Journal of Inorganic Chemistry·Giuseppe ConsiglioSanto Di Bella
Mar 26, 2011·Chemistry : a European Journal·Mitsutaka NakamuraMasato Tanaka
Aug 3, 2011·Chemical Communications : Chem Comm·Boram LeeKay Severin
Sep 3, 2013·Food Chemistry·Sandra PérezEsteve Fàbregas
Oct 8, 2014·European Journal of Medicinal Chemistry·Neng JiangLing-Yi Kong
Feb 23, 2017·Journal of Fluorescence·Shahratul Ain Mohd SukriNurul Huda Abd Karim

❮ Previous
Next ❯

Citations

Jul 17, 2020·Analytical Methods : Advancing Methods and Applications·Sanjeev Kumar KannanMurugavel Kathiresan
Dec 8, 2020·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Muhammad Ameerullah SahudinNurul Huda Abd Karim
Jan 23, 2021·Analytical and Bioanalytical Chemistry·Shibing ChenFafu Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.