PMID: 9161660May 1, 1997Paper

Zolpidem: distinct from triazolam?

The Annals of Pharmacotherapy
B L Lobo, W L Greene

Abstract

To review the literature that compares zolpidem with triazolam, with an emphasis on efficacy and safety in humans. Information was retrieved from a MEDLINE search (1983-1996) of the English-language literature using the terms triazolam and zolpidem. Reports of clinical trials comparing the safety and efficacy of zolpidem and triazolam were included in this review. Data were evaluated according to study design, efficacy, and adverse effects. Pertinent information was selected and the data synthesized into a review format. Zolpidem and triazolam have similar pharmacokinetic and pharmacodynamic effects in humans. Clinical trials have shown that usually recommended, equipotent dosages of zolpidem and triazolam do not differ with respect to pharmacokinetics, efficacy, tolerability, residual effects, memory impairment, rebound insomnia, abuse potential, or other adverse effects. Zolpidem offers no distinct therapeutic advantage over triazolam for the treatment of insomnia.

References

Jan 1, 1992·Journal of Psychoactive Drugs·M B Balter, E H Uhlenhuth
Mar 1, 1992·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·D Wheatley
Jun 1, 1992·The Australian and New Zealand Journal of Psychiatry·D B Menkes
Jan 1, 1990·European Archives of Psychiatry and Clinical Neuroscience·A C AltamuraM G Regazzetti
Jan 25, 1990·The New England Journal of Medicine·J C Gillin, W F Byerley
Dec 1, 1986·British Journal of Clinical Pharmacology·H FriedmanR I Shader
Oct 1, 1986·Journal of Clinical Psychopharmacology·J P PhillipsR B Smith
Sep 1, 1985·The Australian and New Zealand Journal of Psychiatry·R M Rapee
Feb 1, 1974·Journal of Clinical Pharmacology·W VeldkampH V Demissianos
Jan 1, 1983·Psychopharmacology·D R AbernethyR I Shader
Dec 1, 1983·British Journal of Clinical Pharmacology·H R OchsM Knüchel
Nov 1, 1984·Clinical Pharmacology and Therapeutics·G P StoehrR B Smith
Dec 1, 1982·AJR. American Journal of Roentgenology·D SashinR W Simpson
Jan 1, 1995·European Journal of Clinical Pharmacology·N J WesenstenG L Belenky
Aug 1, 1995·Clinical Pharmacology and Therapeutics·S K HukkinenP J Neuvonen
Jan 21, 1995·Lancet·D J GreenblattC E Wright
Jun 1, 1994·Scandinavian Journal of Primary Health Care·J Rosenberg, F Ahlstrøm
Aug 7, 1993·Lancet·R CavallaroE Smeraldi
May 1, 1994·Clinical Pharmacology and Therapeutics·K T OlkkolaP J Neuvonen
Sep 1, 1995·Clinical Pharmacokinetics·P Salvà, J Costa
Sep 1, 1995·Psychopharmacology·N J WesenstenG L Belenky
Apr 1, 1996·Clinical Pharmacology and Therapeutics·A VarheP J Neuvonen
May 16, 2007·The Journal of Pharmacology and Experimental Therapeutics·Lawrence P CarterJohn D Roache

❮ Previous
Next ❯

Citations

Jun 16, 2000·Journal of the American Geriatrics Society·W A RayP Gideon
Feb 15, 2002·Journal of the American Geriatrics Society·P S WangJ Avorn
Apr 15, 2005·Psychopharmacology·Jaime MeléndezAna M Cárdenas
Mar 1, 2007·Journal of Addiction Medicine·Edward BaruchRafael J Hasbun
Nov 16, 2007·Journal of Geriatric Psychiatry and Neurology·John O Brooks, Jennifer C Hoblyn
May 12, 2011·British Journal of Clinical Pharmacology·Francois ChavantMarie-Christine Pérault-Pochat
Dec 1, 1998·CNS Drug Reviews·David J Sanger, Henri Depoortere
Feb 18, 2004·The Annals of Pharmacotherapy·Leonard R RappaMargaretta L Kearson
Dec 10, 1997·The Annals of Pharmacotherapy·R J Holt, S Allard
Nov 13, 2004·Journal of Clinical Psychopharmacology·Sebastian Schneeweiss, Philip S Wang
Mar 20, 2012·Expert Opinion on Pharmacotherapy·David J Greenblatt, Thomas Roth
Nov 26, 2013·The Cochrane Database of Systematic Reviews·Allison Hirst, Richard Sloan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JAMA : the Journal of the American Medical Association
P D NowellD J Kupfer
The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
James K WalshThomas Roth
Revista médica del Instituto Mexicano del Seguro Social
Alejandro Jiménez-Genchi, Grupo de Estudio ZONIA
© 2021 Meta ULC. All rights reserved