PMID: 9434944Jan 22, 1998Paper

Zoo-FISH with microdissected arm specific paints for HSA2, 5, 6, 16, and 19 refines known homology with pig and horse chromosomes

Mammalian Genome : Official Journal of the International Mammalian Genome Society
R ChaudharyB P Chowdhary

Abstract

Microdissected arm specific paints (ASPs) for human (HSA) chromosomes (Chrs) 2, 5, 6, 16, and 19 were used as probes on pig (SSC) and horse (ECA) metaphase chromosomes. Regions homologous to individual human arms were delineated in the two species studied. Of the ten ASPs used, HSA6 and 16 ASPs showed complete synteny conservation of individual arms as single blocks/ arms both in pig and horse. A similar trend was, in general, also observed for HSA19 ASPs. However, contrary to these observations, synteny conservation of individual arms of HSA2 and HSA5 was not observed in pig and horse. The arm specific painting data, coupled with the available gene mapping data, showed that, although HSA2 corresponded to two arms/chromosomes each in pig and horse, the breakpoint of this synteny in humans was not located at the centromere, but at HSA2q13 band. Similarly, arm specific paints for HSA5 showed that of the two blocks/ chromosomes painted in pig and horse, one corresponded to HSA5q13-pter, the other to HSA5q13-qter. The findings suggest that 5q13 band may also be an evolutionary break point, similar to the one detected on HSA2q13. The microdissected human arm specific painting probes used in the present work provide more accurate and...Continue Reading

References

Apr 1, 1992·Genes, Chromosomes & Cancer·H TeleniusB A Ponder
Apr 1, 1992·Genomics·J W IJdoS T Reeders
Jun 10, 1995·Genomics·S Solinas-ToldoR Fries
Sep 1, 1994·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·J WienbergC Lengauer
May 1, 1994·Mammalian Genome : Official Journal of the International Mammalian Genome Society·C MellinkJ Gellin
Mar 1, 1994·Mammalian Genome : Official Journal of the International Mammalian Genome Society·B P ChowdharyI Gustavsson
Aug 1, 1993·Human Molecular Genetics·X Y GuanP S Meltzer
Dec 1, 1995·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·G RettenbergerH Hameister
Jan 1, 1996·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·S MüllerN Archidiacono
Apr 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·L FrönickeI Gustavsson
Apr 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·B P ChowdharyH Scherthan
Dec 1, 1995·Current Opinion in Genetics & Development·J Wienberg, R Stanyon
Apr 1, 1996·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·T RaudseppB P Chowdhary
Mar 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·D MilanJ Gellin
Feb 1, 1997·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·H HameisterK Christensen
Jun 1, 1997·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·L Frönicke, H Scherthan

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Citations

Sep 24, 2005·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Candice Brinkmeyer-LangfordBhanu P Chowdhary
Sep 18, 2007·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·P MusilovaJ Rubes
Aug 31, 2001·ILAR Journal·Nikolai B. Rubtsov
Dec 30, 1999·Genome Research·A R CaetanoJ D Murray
Nov 9, 2005·Cytogenetic and Genome Research·M GrossA Weise
Jul 19, 2021·Gene·Knud Larsen

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