Zoon's balanitis successfully treated with photodynamic therapy: Case report and literature review

Photodiagnosis and Photodynamic Therapy
Francesco BorgiaSerafinella P Cannavò

Abstract

Zoon's balanitis (ZB) is an idiopathic chronic condition usually presenting as a solitary erythematous plaque on the glans of primarily uncircumcised, middle-aged to older men. The different treatment options for this condition often achieve partial results, with frequent recurrence after treatment withdrawal. Recently, photodynamic therapy (PDT) has been proposed as therapeutic option with discordant results. We treated a thirty-five year-old man affected by Zoon's balanitis, resistant to conventional treatments, with 3 sessions of topical ALA-PDT at two weeks intervals. At the end of the treatment period notable improvement of clinical features was observed, with almost complete clearance at 3 months' follow-up, high safety profile and absence of durable side-effects.

References

Oct 27, 2001·Clinical and Experimental Dermatology·C B Bunker
Nov 28, 2002·The American Journal of Dermatopathology·Wolfgang WeyersCarlos Diaz-Cascajo
Dec 22, 2004·Archives of Dermatology·Jorge Santos-JuanesJorge Soto
Jan 24, 2008·International Journal of Dermatology·F BardazziR Balestri
Sep 6, 2012·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Pier Giacomo Calzavara-PintonUNKNOWN Italian Group For Photodynamic Therapy
Jan 18, 2014·Dermatology : International Journal for Clinical and Investigative Dermatology·A KyriakouD Sotiriadis

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Citations

Nov 29, 2016·Indian Journal of Sexually Transmitted Diseases and AIDS·Surabhi Dayal, Priyadarshini Sahu
Feb 1, 2018·Biomedicines·Francesco BorgiaSerafinella P Cannavò
Aug 22, 2017·International Journal of Immunopathology and Pharmacology·Francesco BorgiaSerafinella Patrizia Cannavò
Apr 3, 2020·Dermatologic Therapy·Claudio ConfortiCaterina Dianzani
Aug 4, 2018·Indian Journal of Dermatology, Venereology and Leprology·Francesco BorgiaSerafinella P Cannavò

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