Zwitterionic Amphiphilic Homopolymer Assemblies

Polymer Chemistry
Rajasekhar R RamireddyS Thayumanavan

Abstract

Zwitterionic amphiphilic homopolymers can be conveniently prepared in one-pot using activated ester-based polymer precursors. We show that these zwitterionic polymers can (i) spontaneously self-assemble to form micelle-like and inverse micelle-like assemblies depending on the solvent environment; (ii) act as hydrophilic and hydrophobic nanocontainers in apolar and polar solvents respectively; (iii) undergo pH-responsive surface charge and size variations; (iv) exhibit least cytotoxicity compared to structurally analogous amphiphilic homopolymers.

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Citations

Aug 27, 2019·Polymer Chemistry·Huan HeS Thayumanavan
Apr 24, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Ujjawal Bairagi, Josemon Jacob
Jul 12, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Mingrui LiaoJian Zhou
Sep 9, 2020·Biomacromolecules·Adrian MorenoGerard Lligadas

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